ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

Ig heavy chain V-III region J606

Intramolecular
Cysteine 22 and cysteine 98
A redox-regulated disulphide may form within Ig heavy chain V-III region J606 between cysteines 22 and 98 (22 and 92 respectively in this structure).

Details

Redox score ?
82
PDB code
2dlf
Structure name
high resolution crystal structure of the fv fragment from an anti-dansyl switch variant antibody igg2a(s) crystallized at ph 6
Structure deposition date
1998-12-17
Thiol separation (Å)
2
Half-sphere exposure sum ?
84
Minimum pKa ?
nan
% buried
nan
Peptide accession
P01801
Residue number A
22
Residue number B
98
Peptide name
Ig heavy chain V-III region J606

Ligandability

Cysteine 22 of Ig heavy chain V-III region J606

Cysteine 98 of Ig heavy chain V-III region J606

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